بررسی فعالیت آنتی‌اکسیدنی سطوح مختلف خارشتر (Alhaghi maurorum L) بر عملکرد و متابولیت‌های سرم خون جوجه شترمرغ‌های 9 تا 15هفته

نوع مقاله : مقاله پژوهشی

نویسندگان

گروه علوم دامی، دانشکده کشاورزی، دانشگاه زابل، زابل، ایران

10.22034/aej.2022.361904.2883

چکیده

پژوهش حاضر با‌هدف بررسی فعالیت آنتی‌اکسیدانی و جایگزینی سطوح مختلف خارشتر (Alhaghi maurorum L) با یونجه بر عملکرد و متابولیت‌های سرم خون جوجه شترمرغ‌های 9 تا 15هفته صورت گرفت. در این پژوهش تعداد 36 قطعه شترمرغ با سن 9 هفتگی، از بین شترمرغ‌های پژوهشکده دام‌های خاص دانشگاه زابل در قالب طرح کاملاً تصادفی با 6 گروه آزمایشی شامل؛ سطوح 20، 40، 60، 80 و 100 درصد خارشتر و بدون خارشتر (شاهد) و 6 قطعه شترمرغ در هر تیمار به مدت 6 هفته انجام پذیرفت . نتایج حاصل از این تحقیق نشان داد که مقادیر سرمی گلوکز خون گروه‌های موردمطالعه، با افزایش سطح خارشتر کاهش یافت (0/05≥P). سطوح متفاوت خارشتر بر فعالیت آنزیم‌هایALT ، ALP، LDH و AST معنی‌دار بود (0/05≥P). میزان کلسترول‌تام، تری‌گلیسرید، VLDL-C، LDL-C و HDL-C نسبت به گروه شاهد معنی‌دار‌ شد (0/05≥P). بر اساس نتایج به‌دست‌آمده، ضریب تبدیل غذایی در بین تمام تیمارها آزمایشی معنی‌دار بود (0/05≥P). اعمال تیمارهای آزمایشی بر روی آلبومین سرم خون 32 درصد و بر روی پروتئین تام سرم خون 16 درصد نسبت به شاهد کاهش نشان داد (0/05≥P). میزان MDA پلاسما به‌عنوان شاخص پراکسیداسیون لیپیدی، تحت تأثیر سطوح مختلف خارشتر قرار گرفت (0/05≥P). هم چنین با افزایش سطح خارشتر میزان منیزیم پلاسما از نظر آماری معنی‌دار ‌شد (0/05≥P). به طور کلی می توان گفت گیاه خارشتر خاصیت ضد دیابتی دارد و مواد موثره موجود در آن از طریق کاهش میزان گلوکز سرم خون باعث کاهش تولید رادیکال های آزاد و بهبود وضعیت استرس‌اکسیداتیو می‌شود.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The effect of feeding different levels of camels- thorn (Algaghi maurorum L) replacement on anti-diabetic serum factors in ostriches 9 to 15 weeks

نویسندگان [English]

  • Hosein Moradgholi
  • Kamal Shojaeian
  • Ghasem Jalilvand
  • Farzad Bagherzade Kasmani
  • Mahmood Ghazaghi
Department of Animal Science, Faculty of Agriculture, Zabol University, Zabol, Iran
چکیده [English]

The present study was conducted with the aim of investigating the antioxidant activity and replacing different levels of Alhaghi maurorum L with alfalfa on the performance and blood serum metabolites of 9- to 15-week-old ostrich chicks. In this research, 36 pieces of ostriches with the age of 9 weeks, from among the ostriches of the special livestock research institute of Zabul University in the form of a completely random design with 6 experimental groups including; 20, 40, 60, 80 and 100% itchy and non-itchy levels (control) and 6 pieces of ostrich in each treatment for 6 weeks. The results of this research showed that the blood glucose levels of the studied groups decreased with the increase in the level of scabies (P≥0.05). Different levels of itch were significant on the activity of ALT, ALP, LDH and AST enzymes (P≥0.05). The amount of cholesterol, triglyceride, VLDL-C, LDL-C, and HDL-C was significant compared to the control group (P≥0.05). Based on the obtained results, the food conversion ratio was significant among all experimental treatments (P≤0.05). The application of experimental treatments showed a 32% decrease in blood serum albumin and a 16% decrease in total blood serum protein compared to the control (P≥0.05). Plasma MDA as an index of lipid peroxidation was affected by different levels of scabies (P≥0.05). Also, with the increase in scabies level, plasma magnesium level was statistically significant (P≥0.05). In general, it can be said that the scurvy plant has anti-diabetic properties and its active ingredients reduce the amount of glucose in the blood serum and reduce the production of free radicals and improve the oxidative stress.

کلیدواژه‌ها [English]

  • Oxidativestress
  • camels- thorn
  • Diabetes
  • Blood biochemistry

مراجع

  1. Sadeghi, M. and Zarei, M.A., 2020. Evaluation of Antioxidant Activity and Determination of Phenol and Flavonoids in Hexane Extract of Aerial Plants Descurainia sophia and Fumaria vaillantii. Journal of Plant Research (Iranian Journal of Biology). 33(2): 365-373. (In Persian)
  2. Unuofin, J.O. and Lebelo, S., 2020. Antioxidant Effects and Mechanisms of Medicinal Plants and Their Bioactive Compounds for the Prevention and Treatment of Type 2 Diabetes: An Updated Review. Oxidative Medicine and Cellular Longevity. 36: 135-143.
  3. Davignon, J., Jacob, R.F. and Mason, R.P., 2004. The antioxidant effects of statins. Coron Artery Dis. 8: 251-258.
  4. Maraki, H., Sepehry, A. and Mofidabadi, A.J., 2017. Studying the effects of media and micro-explants on optimization of Alhagi camelorum culture. Iranian Journal of Rangelands and Forests Plant Breeding and Genetic Research. 25(1): 148-159. (In Persian)
  5. Dhaniya, S. and Parihar, S.K., 2019. Evaluation of antioxidant potential of Dicoma tomentosa and Alhagi maurorum leaf and stem powder. Journal of Drug Delivery and Therapeutics. 5: 207-211.
  6. Urabee, M.C., Abdulsattar, J.O., Nasif, Z.N. and Al Garawi, Z.S., 2022. Extraction methods of Alhagi Maurorum (camel thorn) and its therapeutic applications. Journal of Physics: Conference Series. 8: 1853-1861.
  7. Kongnum, K. and Hong, P.T., 2012. Effect of Lactobacillus plantarum isolated from digestive tract of wild shrimp on growth and survival of white shrimp (Litopenaeus vannamei) challenged with Vibrio harveyi. Fish and Shellfish Immunology. 8: 170-177.
  8. Ahmed, Z.A.M., Aljakee, J.K. and Elhady, M., 2014. Ostriches as an alternative promising industry to animal and poultry meat. International Conference Challenges in Poultry Industry, Giza, Egypt. 1- 4.
  9. Zhang, R., Ling, L., Han, D., Wang, H., Yu, G., Jiang, L. and Chang, Z., 2019. FEM analysis in excellent cushion characteristic of ostrich (Struthio camelus) toe pads. Plos one. 14(5): e0216141.‏
  10. Sulaiman, G.M., 2013. Antimicrobial and cytotoxic activities of methanol extract of Alhagi maurorum. African Journal of Microbiology Research. 10: 1548-1557.
  11. Alicia, A. and Xavier, F.M., 2014. Ostrich Meat: Nutritional, Breeding, and Consumption Aspects. Journal of Food and Nutrition Research. 6: 301-305.
  12. Browmlee, M., 2001. Biochemistry and molecular cell biology of diabetic complications. Nature. 813-820
  13. Polawska, J., Marchewka, J., Cooper, R.G., Sartowksa, K., Pomianowski, J. and Józwik, A., 2011. The ostrich meat - an updated review. Animal Science Papers and Reports. 89-97.
  14. Harte, R., Norton, L., Whitehouse, C., Lorincz, I., Jones, D. and Gerald, N., 2022. Design of a randomized controlled trial of digital health and community health worker support for diabetes management among low income patients. Journal of the Contemporary Clinical Trials Communications. 1- 8.
  15. De Vries, A.S., Verbeuren, T.J., Van de Voorde, J., Lameire, N.H. and Vanhoutte, P.M., 2000. Endothelial dysfunction in diabetes, Br J Pharmacol. 130: 963-974.
  16. Manny, S., 2017. American Diabetes Association Takes an Ostrich Approach to Brittle Diabetes. Journal of Brittle Diabetes Foundation. 14: 40-55.
  17. Urabee, M.C., Abdulsattar, J.O., Nasif, Z.N. and Al Garawi, Z.S., 2022. Extraction methods of Alhagi Maurorum (camel thorn) and its therapeutic applications. Journal of Physics: Conference Series. 8: 1853-1861.
  18. Brand, T. and Olivier, A., 2011. Ostrich Nutrition and Welfare. In: Glatz, P.C., Lunam, C. and Malecki, I., (ed), The Welfare of farmed ratites, (Berlin, Heidelberg, Germany: Springer-Verlag). 91-109.
  19. Ghasemi, H. and Hajkhodadadi, I., Metabolic profile and antioxidant status of ostriches receiving water supplemented with essential oil mixture of Zataria multiflora, Mentha piperita, Foeniculum vulgare and Eucalyptus globules. Iranian Journal of Medicinal and Aromatic Plants Research. 35(1): 12-24. (In Persian)
  20. Buege, J.A. and Aust, S.D., 2002. Microsomal lipid peroxidation. Meth in Enzymol. 13: 302-310.
  21. Mashayikhi, K. and Atashi, p., 2013. Guide to Plant Physiology Experiments, first edition, Vaggan Sirang Publications. (In Persian)
  22. Matsui, H., Ban-Tukuda, T. and Wakita, M., 2009. Detection of fiber-digesting bacteria in ceca of ostrich using specific primer sets. Curr Microbiol. 60(2): 112-116.
  23. Arjabi, A., Anarjan, N. and Jafarizadeh Malmiri, H., 2021. Effects of extracting solvent composition on antioxidant and antibacterial activities of Alhagi maurorum Journal of Food Processing and Preservation. 45(3): 10-11.
  24. Ahmad, S., Riaz, N., Saleem, M., Jabbar, A., Nisar, U.R. and Ashraf, M., 2010. Antioxidant flavonoids from Alhagi maurorum. Journal of Asian Natural Products Research. 12(2): 138-143.
  25. Asadi Moghadam, O. and Nobakht, A., 2017. The effects of using different levels of alfalfa and alhaji with and without enzyme on performance, carcass traits and blood biochemical parameters of broilers. Animal Sciences Journal. 30(115): 179-192.‏ (In Persian)
  26. Samuel Lozano, S., Armando, M., De, A., Raúl Ortiz, M., Teódulo, Q.T., Eduardo Morales, B., Omar Francisco, P.R. and Arturo Gerardo, V.F., Effect of the inclusion of corn silage in the apparent digestibility of ostrich (Struthio camelus, Var. Domesticus) diets. Tecnica Pecuaria en Mexico. 46(1): 79-90.
  27. Kazemi, M. and Saleh, H., In vitro evaluation of medicinal plants including Artemisia aucheri Boiss, Salvia leriifolia Benth, Achilea santolina, and Nepeta glumerulosa in livestock diet. Journal of Animal Environment. 13(1): 81-92. (In Persian)
  28. Ocat, N., Erener, G., Burak Ak, F., Sungu, M., Altop, A. and Ozmen, A., 2008. Performance of broilers fed diets supplemented with dry peppermint (Mentha piperita) or thyme (Thymus vulgaris L.) leaves as growth promoter source. Journal of Czech Journal of Animal Science. 53(4): 169-176.
  29. Mehri, M., Sabaghi, V. and Bagherzadeh-Kasmani, F., 2015. Mentha piperita (peppermint) in growing Japanese quails’ diet: Serum biochemistry, meat quality, humoral immunity. Journal of Animal Feed Science and Technology. 206: 57-66.
  30. Cross, D.E., McDevitt, R.M., Hillman, K.T. and Camovic, T.A., 2007. The effect of herbs and their associated essential oils on performance, dietary digestibility and gut microflora in chickens from 7 to 28 days of age. British Poultry Science. 11: 496-506.
  31. Khazaie, S., Karami, M. and Palizdar, M.H., Effect of feeding different levels of Echinacea extract on growth performance, blood metabolites, immune system and cortisol secretion in Japanese quails. Journal of Animal Environment. 14(1): 121-128. (In Persian)
  32. Nabiyouni, F., Vaezi, G., Malekirad, A.A. and Abdollahi, M., 2016. The effects of ethanol extract of Alhagi camelorum on hepatic and renal functions in streptozotocin-induced diabetic rats.Experimental animal Biology. 5(1): 31-38. (In Persian)
  33. Cilliers, S.C., 1998. Feedstuff evaluation, metabolizable energy and amino acid requirements for maintenance and growth in ostriches. In Proc. 2nd International Ratite Conference, 21-13 September, Oudtshoorn.
  34. Div-salaar, K., Saravani, R., Shamsi-e-meimandi, M., Taei, M. and Sheikholeslami A., Electrophoretic Profile of Albumin, α1, α2, β and γ Globulin in Sera of Opioid Dependants and Non-dependants. Yafteh. 9(4): 13-19. (In Persian)
  35. Abadi, S., Nazaifi, H., Mehri, M. and Mohammadi, R., Investigating native poultry serum proteins by electrophoresis. Journal of Veterinary Research. 52(1): 29-43.
  36. Gobbi, P.G., Gendarini, A., Crema, A., Cavalli, C., Attardo‐Parrinello, G., Federico, M. and Ascari, E., 1985. Serum albumin in Hodgkin's disease. Cancer. 55: 389-393.
  37. Lee, A.Y., Cassar, P.M., Johnston, A.M. and Adelstein, S., 2017. Clinical use and interpretation of serum protein electrophoresis and adjunct assays. Br. J. Hosp. Med. 78: C18-C20.
  38. Kyle, R., Katzmann, J., Lust, J. and Dispenzieri, A., 2002. Clinical indications and applications of electrophoresis and immunofixation. Manual of Clinical Immunology, Sixth Edition. 66-67.
  39. Yagoubian, F., Cheraghi, J. and Mahmoudi, M., 2013. Investigating the protective effect of the hydroalcoholic extract of the aerial parts of Alhaji Maurorum against acute nephrotoxicity induced by gentamicin in rats. Scientific Research Journal of Ilam University of Medical Sciences. 2-22. (In Persian)
  40. Baradaran, A., Madihi, Y., Merrikhi, A., Rafieian, K.M. and Nasri, H., 2013. Serum lipoprotein (a) in diabetic patients with various renal function not yet on dialysis. Pakistan Journal of Medical Sciences. 4: 354-357. (In Persian)
  41. Membrez, M., Blancher, F., Jaquet, M., Bibiloni, R. and Cani, P.D., 2008. Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in mice. FASEB Journal. 11: 2416-2426.
  42. Poodineh Moghadam, M., shahdadi, H., bamari, F., khammari, M. and mir, E., Evaluation of Serum Magnesium Level in Patients with Type 2 Diabetes. J Diabetes Nurs. 2(2): 52-62. (In Persian)
  43. Sheweita, S.A., Mashaly, S., Newairy, A.A., Abdou, H.M. and Eweda, S.M., 2016. Changes in Oxidative Stress and Antioxidant Enzyme Activities in Streptozotocin-Induced Diabetes Mellitus in Rats: Role of Alhagi maurorum Journal of the Oxidative Medicine and Cellular Longevity. 9: 1-8.
  44. Bonnefont, R.D., 2004. The role of antioxidant micronutrients in the prevention of diabetic complications. Treatment in Endocrinology. 3: 41-52.
  45. Shim, K.S., Park, G.H., Choi, C.J. and Nac, S., 2004. Decreased triglyceride and cholesterol levels in serum, liver and breast muscle in broiler by the supplementation of dietary Codonopsis lanceolata root. Asian-Australian Journal of Animal Science. 511-513.
فصلنامه محیط زیست جانوری
دوره 15، شماره 3
آبان 1402
صفحه 119-128

فایل ها

هم رسانی

ارجاع به این مقاله

آمار